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Meldrumacid or 2,2-dimethyl-1,3-dioxane-4,6-dione is an organic compound. The compound was first made in 1908 by Andrew Norman Meldrum by a condensation reaction of malonic acid with acetone in acetic anhydride and sulfuric acid. As an alternative to its original preparation, Meldrumacid can be synthesized from malonic acid, isopropenyl acetate, and catalytic sulfuric acid.